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Nix can be a huge pain to use, and with the recent redesign it somehow feels even more disjointed than before. But it's still one of my favorite pieces of software. I think a clean interface like https://devenv.sh/ could make all the difference (havent tried it yet but looks promising).
That said, if I understand you correctly, I think nix does let you do what you're describing. You can make an overlay, which is a way to modify a set of packages by reaching in and changing build instructions or add packages to the set. So, you can make an overlay of nixpkgs and add a modified libgcc called mylibgcc to the set. In the same overlay, you can modify package A and package B that depend on libgcc, and change their build instructions, including making them use mylibgcc as a build dependency. If you do this for then both packages will use mylibgcc as a single shared dependency without duplicating it.
Im on mobile but could try to send a working example if you need one, lmk.
Some references:
https://nixos.wiki/wiki/Nixpkgs/Modifying_Packages
https://nixos.wiki/wiki/Overlays
I get what you mean, but keep in mind that for every distro you're reliant on the community to get nvidia support integrated. Also if you only have few apps that require it, then the nixGL flake is not bad. https://github.com/guibou/nixGL
Depending on your use case, devbox (https://github.com/jetpack-io/devbox) could be what you're looking for. It is powered by Nix, but abstracts the nix language away, so that you can use it like a "regular" package manager.
Currently it works on a "per-project" basis, but we're planning to add support to use it as your primary package manager for global installs as well.
